1 Result for "

CL118326

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CL118326" in MCE Product Catalog:

Cat. No.: HY-182434
CAS No.: 97012-61-8
Target:  

Phosphatase FAP

Research Areas:  

Inflammation/Immunology

CL 118326 is a potent, selective, competitive inhibitor of mammalian pancreatic phospholipase A2 (PLA2) and a weak antagonist of platelet-activating factor receptor (PAF receptor). CL 118326 competitively inhibits mammalian pancreatic PLA2 (porcine: IC50 = 1.55 μg/mL), and shows no activity against snake venom or bee venom PLA2. CL 118326 inhibits PAF-induced and thrombin-induced platelet aggregation, as well as the release of leukotriene (LTC4) and histamine from basophil-enriched leukocytes. CL 118326 can be used for research on inflammation and allergic reactions .
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