2 Results for "

COV504

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "COV504" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-138293
CAS No.: 2417302-07-7
Purity:  99.33%
Synonyms: CDK7-IN-3
Target:  

CDK Apoptosis

Research Areas:  

Cancer

SY-5609 (CDK7-IN-3) is an orally active, highly selective, noncovalent CDK7 inhibitor with a KD of 0.065 nM. SY-5609 shows poor inhibition on CDK2 (Ki=2600 nM), CDK9 (Ki=960 nM), CDK12 (Ki=870 nM). SY-5609 induces apoptosis in tumor cells and has antitumor activity .
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Cat. No.: HY-156920
CAS No.: 158983-23-4
Target:  

Necroptosis RIP kinase

Research Areas:  

Inflammation/Immunology Cancer

VDX-111 is an analog of vitamin D. VDX-111 exhibits cytotoxicity in ovarian cancer cells through upregulation of RIPK1/RIPK3 pathway and induction of necroptosis. VDX-111 promotes expressions of cytokines and exhibits antitumor activity in mouse model .
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