158983-23-4
158983-23-4
Chemical Structure
VDX-111
- CAS No.: 158983-23-4
- Formula:C29H45BrO4
- Molecular Weight:537.57
InChIKey: SLFLGLKEAANGNN-RBDVLXGPSA-N
SMILES: C[C@]([C@@]1([H])[C@H](C)CCCC(C)(O)C)(CCC/2)[C@](CC1)([H])C2=C\C=C(C([C@H]3O)=C)\C[C@H](C3)OC(CBr)=O
Biological Activity: VDX-111 is an analog of vitamin D. VDX-111 exhibits cytotoxicity in ovarian cancer cells through upregulation of RIPK1/RIPK3 pathway and induction of necroptosis. VDX-111 promotes expressions of cytokines and exhibits antitumor activity in mouse model[1].
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VDX-111 | VDX-111 is an analog of vitamin D. VDX-111 exhibits cytotoxicity in ovarian cancer cells through upregulation of RIPK1/RIPK3 pathway and induction of necroptosis. VDX-111 promotes expressions of cytokines and exhibits antitumor activity in mouse model. | |||||||||||||||||||||
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