1 Result for "

CT 179

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CT 179" in MCE Product Catalog:

Cat. No.: HY-179078
CAS No.: 1996636-69-1
Target:  

OLIG2 Apoptosis Caspase PARP

Research Areas:  

Neurological Disease Cancer

CT-179 is a brain-penetrant and orally active OLIG2 inhibitor with a human IC50 of 1250 nM. CT-179 disrupts OLIG2 dimerization, phosphorylation, and DNA binding, blocking OLIG2-driven transcription. CT-179 induces G2/M phase arrest and increases G0 population. CT-179 induces apoptosis by reducing anti-apoptotic proteins and increasing cleaved caspase-3 and cleaved PARP. CT-179 can be used for the research of subgroup medulloblastoma .
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