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Pathways Recommended: Antibody-drug Conjugate/ADC Related
Results for "

Computer-aided drug design

" in MedChemExpress (MCE) Product Catalog:
Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-179177
    AO-365/43472821

    		DYRK CDK Tau Protein Amyloid-β Neurological Disease
    AO-365/43472821 is a selective, brain-penetrant Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitor (IC50 = 0.29 μM) and shows a significant inhibitory effect on (CDC-like kinase 1) CLK1 (IC50 = 0.08 μM). AO-365/43472821 could protect the human neuroblastoma cell line SH-SY5Y from Okadaic acid (HY-N6785) (OA)-induced injury. AO-365/43472821 decreased tau (pSer396)/tau and Aβ1-42 protein expression. AO-365/43472821 can be used for the study of Alzheimer's disease .
    AO-365/43472821
  • HY-160985
    Lemidosul

    		Parasite Others
    Lemidosul is an anti-trypanosomiasis compound that can be further optimized for its performance as an anti-trypanosomiasis drug by means of a computer-aided drug design (CADD) approach .
    Lemidosul
  • HY-149423
    PI5P4K-β-IN-1

    		PI5P4K Cancer
    PI5P4K-β-IN-1 (compound vs1) is a potent inhibitor of PI5P4K-β (IC50: 0.80 μM) .
    PI5P4K-β-IN-1

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