3 Results for "

Computer-aided drug design

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Computer-aided drug design" in MCE Product Catalog:

Cat. No.: HY-179177
CAS No.: 1081122-55-5
Research Areas:  

Neurological Disease

AO-365/43472821 is a selective, brain-penetrant Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitor (IC50 = 0.29 μM) and shows a significant inhibitory effect on (CDC-like kinase 1) CLK1 (IC50 = 0.08 μM). AO-365/43472821 could protect the human neuroblastoma cell line SH-SY5Y from Okadaic acid (HY-N6785) (OA)-induced injury. AO-365/43472821 decreased tau (pSer396)/tau and Aβ1-42 protein expression. AO-365/43472821 can be used for the study of Alzheimer's disease .
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Cat. No.: HY-160985
CAS No.: 88041-40-1
Target:  

Parasite

Research Areas:  

Others

Lemidosul is an anti-trypanosomiasis compound that can be further optimized for its performance as an anti-trypanosomiasis drug by means of a computer-aided drug design (CADD) approach .
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Cat. No.: HY-149423
CAS No.: 332407-28-0
Target:  

PI5P4K

Research Areas:  

Cancer

PI5P4K-β-IN-1 (compound vs1) is a potent inhibitor of PI5P4K-β (IC50: 0.80 μM) .
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