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Cortisol (Standard)

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

5

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0583R
    Hydrocortisone (Standard)
    Maximum Cited Publications
    85 Publications Verification

    Cortisol (Standard)

    		 Reference Standards Glucocorticoid Receptor Endogenous Metabolite Inflammation/Immunology Endocrinology Cancer
    Hydrocortisone (Standard) is the analytical standard of Hydrocortisone. This product is intended for research and analytical applications. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .
    Hydrocortisone (Standard)
  • HY-17461R
    Cortisone (Standard)
    3 Publications Verification

    17-Hydroxy-11-dehydrocorticosterone(Standard); Kendall's compound E (Standard)

    		 Reference Standards Glucocorticoid Receptor Endogenous Metabolite Inflammation/Immunology Endocrinology
    Cortisone (Standard) is the analytical standard of Cortisone. This product is intended for research and analytical applications. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations .
    Cortisone (Standard)
  • HY-17461AR
    Cortisone acetate (Standard)
    3 Publications Verification

    Cortisone 21-acetate (Standard)

    		 Reference Standards Glucocorticoid Receptor Endogenous Metabolite Inflammation/Immunology Endocrinology
    Cortisone acetate (Standard) is the analytical standard of Cortisone acetate. This product is intended for research and analytical applications. Cortisone acetate (Cortisone 21-acetate), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acetate acts as an immunosuppressant and anti-inflammatory agent. Cortisone acetate can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations .
    Cortisone acetate (Standard)
  • HY-B1265R
    Hydrocortisone 17-valerate (Standard)

    Cortisol 17-valerate (Standard)

    		 Glucocorticoid Receptor Reference Standards Others
    Hydrocortisone 17-valerate (Standard) is the analytical standard of Hydrocortisone 17-valerate. This product is intended for research and analytical applications. Hydrocortisone 17-valerate (Cortisol 17-valerate) is a thiazolidine compound .
    Hydrocortisone 17-valerate (Standard)
  • HY-N8460AR
    Cortisol sulfate sodium (Standard)

    Cortisol 21-sulfate sodium (Standard)

    		 Reference Standards Endogenous Metabolite Endocrinology
    Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate sodium is a specific ligand for intracellular transcortin .
    Cortisol sulfate sodium (Standard)
  • HY-B0983R
    Hydrocortisone 17-butyrate (Standard)

    Cortisol 17-butyrate (Standard); Hydrocortisone butyrate (Standard)

    		 Reference Standards Adrenergic Receptor Inflammation/Immunology Endocrinology
    Hydrocortisone 17-butyrate (Standard) is the analytical standard of Hydrocortisone 17-butyrate. This product is intended for research and analytical applications. Hydrocortisone 17-butyrate is a non-fluorinated topical corticosteroid for use in psoriasis, eczema, and other inflammatory dermatoses. Hydrocortisone 17-butyrate inhibits granuloma formation in rats. Hydrocortisone 17-butyrate can induce vasoconstriction .
    Hydrocortisone 17-butyrate (Standard)
  • HY-B1183R
    Hydrocortisone acetate (Standard)

    Hydrocortisone 21-acetate(Standard); Cortisol 21-acetate (Standard)

    		 Reference Standards Glucocorticoid Receptor Endogenous Metabolite Inflammation/Immunology Endocrinology
    Hydrocortisone acetate (Standard) is the analytical standard of Hydrocortisone acetate. This product is intended for research and analytical applications.
    Hydrocortisone acetate (Standard)
  • HY-18056R
    PF-915275 (Standard)

    		11β-HSD Metabolic Disease
    PF-915275 (Standard) is the analytical standard of PF-915275. This product is intended for research and analytical applications. PF-915275 is a potent, selective and orally active human 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor with a Ki of 2.3 nM and an EC50 of 15 nM (in HEK293 cells). The dose-dependent effect of PF-915275 on conversion of cortisone to cortisol in primary human and monkey hepatocytes, with an EC50 of 20 and 100 nM, respectively .
    PF-915275 (Standard)
  • HY-12502AR
    Efonidipine hydrochloride monoethanolate (Standard)

    NZ-105 hydrochloride monoethanolate (Standard); (±)-Efonidipine hydrochloride monoethanolate (Standard)

    		 Reference Standards Calcium Channel SARS-CoV Cardiovascular Disease
    Efonidipine (NZ-105) hydrochloride monoethanolate (Standard) is the analytical standard of Efonidipine hydrochloride monoethanolate (HY-12502AR). This product is intended for research and analytical applications. Efonidipine (NZ-105) hydrochloride monoethanolate is an orally active dual L-type and T-type calcium channel blocker (CCB) with IC50 values of 1.8 and 350 nM, respectively. Efonidipine hydrochloride monoethanolate inhibits SARS-CoV-2 main protease. Efonidipine hydrochloride monoethanolate modulates adrenal steroidogenesis by increasing the expression of steroidogenic acute regulatory protein (StAR), dbcAMP-or angiotensin II-induced StAR mRNA expression and DHEA-S production, while suppressing the biosynthesis of aldosterone and cortisol. Efonidipine hydrochloride monoethanolate reduces plasma aldosterone levels in vivo. Efonidipine hydrochloride monoethanolate improves cardiac function in heart failure models by inhibiting T-type calcium channels (via both tonic and use-dependent blockade), independently of blood pressure reduction. Efonidipine hydrochloride monoethanolate can be used for research in hypertension, heart failure, and disorders involving dysregulated steroid hormone synthesis .
    Efonidipine hydrochloride monoethanolate (Standard)
  • HY-105656R
    Hydrocortisone phosphate sodium (Standard)

    Hydrocortisone 21-phosphate sodium (Standard); Cortisol 21-phosphate sodium (Standard)

    		 Phosphatase Reference Standards Infection
    Hydrocortisone phosphate sodium (Standard) is the analytical standard of Hydrocortisone phosphate sodium (HY-105656). This product is intended for research and analytical applications. Hydrocortisone phosphate sodium is a soft steroid with low anti-inflammatory properties and a short duration of action. Hydrocortisone phosphate sodium can be used for the research for several ocular conditions and gastric ulcers .
    Hydrocortisone phosphate sodium (Standard)
  • HY-108618R
    BC11-38 (Standard)

    		Reference Standards Phosphodiesterase (PDE) Endocrinology
    BC11-38 (Standard) is the analytical standard of BC11-38 (HY-108618). This product is intended for research and analytical applications. BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC50s of 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells .
    BC11-38 (Standard)

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