1852-36-4
Chemical Structure
Cortisol sulfate sodium
Synonym(s): Cortisol 21-sulfate sodium
- CAS No.: 1852-36-4
- Formula:C21H29NaO8S
- Molecular Weight:464.50
IUPAC Name: sodium 2-((8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl sulfate
InChIKey: DJKQHUMDQFOLHE-WDCKKOMHSA-M
SMILES: C[C@]([C@@]1(O)C(CO[S](=O)(O[Na])=O)=O)(C2)[C@](CC1)([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(CC4)C)([H])[C@H]2O
Biological Activity: Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate sodium is a specific ligand for intracellular transcortin[1][2][3].
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Cortisol sulfate sodium | 99.79% | Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate sodium is a specific ligand for intracellular transcortin. | ||||||||||||||||||||
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Cortisol sulfate sodium (Standard) | ≥98% | Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate sodium is a specific ligand for intracellular transcortin. | ||||||||||||||||||||
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Cortisol sulfate-d4 sodium | Cortisol-21-sulfate-d4 (sodium) is the deuterium labeled Cortisol-21-sulfate. | |||||||||||||||||||||
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References
- [1]. C S Hall, et al. Simultaneous metabolism of cortisol sulfate and cortisol in normal human adults. J Clin Endocrinol Metab. 1970 Oct;31(4):439-44. [Content Brief]
- [2]. S S Singer, et al. Enzymatic sulfation of steroids: I. The enzymatic basis for the sex difference in cortisol sulfation by rat liver preparations. Endocrinology. 1976 Apr;98(4):963-74. [Content Brief]
- [3]. T Hayashi, et al. Cortisol-21-sulfate (FS) is a specific ligand for intracellular transcortin: demonstration of three types of high affinity corticosteroid binders in bovine aortic cytosol by a combined use of FS and RU 28362. Endocrinology. 1990 Jan;126(1):307-16. [Content Brief]
