686770-80-9
686770-80-9
Chemical Structure
BC11-38
- CAS No.: 686770-80-9
- Formula:C15H16N2OS2
- Molecular Weight:304.43
IUPAC Name: 3-phenyl-2-(propylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one
InChIKey: YHNDCCKFNWDQGW-UHFFFAOYSA-N
SMILES: O=C1C2=C(CCS2)N=C(SCCC)N1C3=CC=CC=C3
Biological Activity: BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC50s of 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
BC11-38 | 99.42% | BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC50s of 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
BC11-38 (Standard) | ≥98% | BC11-38 (Standard) is the analytical standard of BC11-38 (HY-108618). This product is intended for research and analytical applications. BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC50s of 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
