IWP L6 (GMP) (Porcn Inhibitor III (GMP)) is IWP L6 (HY-15825) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IWP L6 (Porcn Inhibitor III) is a Porcupine (Porcn) inhibitor with an EC50 of 0.5 nM. IWP L6 disrupts well-established Wnt-dependent developmental processes of embryonic and juvenile zebrafish.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1427782-89-5
- 分子式: C25H20N4O2S2
- 分子量:472.58
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Wnt-C59 (Standard)PORCN Inhibitor -
HY-18988
ETC-159PORCN Inhibitor -
HY-16268
KartogeninChondroprotective Agent -
HY-12238
IWR-1Wnt Signaling Inhibitor -
HY-111472
Porcn-IN-1Porcupine Inhibitor -
HY-14428
ICG-001Apoptosis Inducer -
HY-13912G
IWP-2 (GMP)Wnt Inhibitor (GMP) -
HY-15659G
Wnt-C59 (GMP)PORCN Inhibitor
生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | EC50 |
0.5 nM
Compound: 7; IWP-L6
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Antiproliferative activity against human HeLa cell line assessed as cell growth inhibition
Antiproliferative activity against human HeLa cell line assessed as cell growth inhibition
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[PMID: 33822624] |
体外実験
IWP L6 (Porcn Inhibitor III) (GMP) effectively suppressed the phosphorylation of dishevelled 2 (Dvl2) in HEK293 cells, a biochemical event associated with many Wnt-dependent cellular responses. IWP L6 (GMP) inhibits Wnt mediated branching morphogenesis in cultured embryonic kidneys [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1427782-89-5
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分子量 472.58
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分子式 C25H20N4O2S2
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SMILES
O=C(NC1=NC=C(C2=CC=CC=C2)C=C1)CSC3=NC(CCS4)=C4C(N3C5=CC=CC=C5)=O
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別名
Porcn Inhibitor III (GMP)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
IWP L6 (GMP) 関連分類
HY-15825G 関連分類
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