1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. BC11-38

BC11-38 

Cat. No.: HY-108618 Purity: ≥98.0%
Handling Instructions

BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC50s of 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells.

For research use only. We do not sell to patients.

BC11-38 Chemical Structure

BC11-38 Chemical Structure

CAS No. : 686770-80-9

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Description

BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC50s of 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells[1].

IC50 & Target[1]

PDE11

0.28 μM (IC50)

In Vitro

BC11-38 (20 μM; hours) elevate cAMP levels in H295R adrenocortical cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

304.43

Formula

C₁₅H₁₆N₂OS₂

CAS No.

686770-80-9

SMILES

O=C1C2=C(CCS2)N=C(SCCC)N1C3=CC=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

References

Purity: ≥98.0%

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Keywords:

BC11-38Phosphodiesterase (PDE)cAMPcortisollevelsadrenocorticalcellsproductionInhibitorinhibitorinhibit

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BC11-38
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HY-108618
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