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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
DCN2
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "DCN2" in MCE Product Catalog:
1
1 Cited Publications
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Research Areas:
DI-591 is a potent, high-affinity and cell-permeable inhibitor of the DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with Ki values of 12 nM and 10.4 nM, respectively and has no appreciable binding to DCN3, DCN4, and DCN5 proteins. DI-591 selectively inhibits neddylation of cullin 3 but has no or minimal effect on neddylation of other cullin family members .
Cat. No.: HY-184536
CAS No.: 3085130-99-7
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DCN1 modulator-1 is a DCN1 modulator. DCN1 modulator-1 binds covalently to DCN2. DCN1 modulator-1 induces the expression of fetal hemoglobin mRNA (HBG1) and fetal hemoglobin protein (HbF). DCN1 modulator-1 is applicable to research related to sickle cell disease and thalassemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
