2 Results for "

Davutamig

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Davutamig" in MCE Product Catalog:

Cat. No.: HY-P990073
CAS No.: 2648058-48-2
Synonyms: REGN-5093

Target:  

c-Met/HGFR

Research Areas:  

Cancer

Davutamig (REGN-5093) is a human IgG4-kappa, anti-MET bispecific antibody. Davutamig binds 2 distinct epitopes of MET, blocking ligand binding and inducing MET internalization and degradation. Davutamig is applicable to the research of advanced non-small cell lung cancer with MET gene abnormalities .
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Cat. No.: HY-171191
REGN5093-M114 is a bispecific antibody-drug conjugate (ADC) that targets two epitopes of the MET receptor tyrosine kinase inhibits the proliferation of NSCLC cells, exhibits antitumor efficacy in mouse models. REGN5093-M114 is composed of the human monoclonal anti-MET antibody Davutamig (HY-P990073) and the tubulin-inhibiting linker-payload (HY-148528) .
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