2 Results for "

Defensin HNP-3 human

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Defensin HNP-3 human" in MCE Product Catalog:

Cat. No.: HY-P2302
CAS No.: 136661-76-2
Defensin HNP-3 human is an α-defensin stored in the azurophilic granules of human neutrophils. Defensin HNP-3 human exerts broad-spectrum bactericidal, antifungal and antiviral activities mainly by forming bacterial membrane pores, and acts as a chemoattractant for monocytes and T cells. Defensin HNP-3 human maintains epithelial integrity to support periodontal tissue homeostasis, and exerts concentration-dependent effects on epithelial cell proliferation, adhesion and bacterial adhesion. Defensin HNP-3 human targets solid tumors and leukemia by inducing single-strand DNA breaks and membrane permeabilization in tumor cells via electrostatic binding and pore formation. Defensin HNP-3 human is abundant in human tongue squamous cell carcinoma and neutrophils infiltrating oral squamous cell carcinoma. Defensin HNP-3 human can be applied to research related to periodontitis and human tongue squamous cell carcinoma .
loading...
    loading...
Cat. No.: HY-P76870
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DEFA3; HP-3; Prev. DEF3; Defensin 3, Neutrophil-Specific; HNP-3; Neutrophil Peptide 3; Defensin, Alpha 3, Neutrophil-Specific; Defensin, Alpha 3; Neutrophil Defensin 3; HNP3; Defensin Alpha 3; HP3
Species:  
Source:  
loading...
    loading...