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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Deferasirox
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Deferasirox" in MCE Product Catalog:
14
Target:
Research Areas:
Deferasirox (ICL 670) is an orally available iron chelator used for the management of transfusional iron overload .
Cat. No.: HY-16564
CAS No.: 554435-83-5
Target:
Research Areas:
Deferasirox Fe3+ Chelate is an iron chelating agent extracted from patent WO2003053986 .
Cat. No.: HY-17359S
CAS No.: 1133425-75-8
Cat. No.: HY-17359R
CAS No.: 201530-41-8
Synonyms: ICL 670 (Standard)
Target:
Research Areas:
Deferasirox (Standard) is the analytical standard of Deferasirox. This product is intended for research and analytical applications. Deferasirox (ICL 670) is an orally available iron chelator used for the management of transfusional iron overload .
Cat. No.: HY-W127779
CAS No.: 554445-58-8
Cat. No.: HY-17359S1
CAS No.: 1261392-79-3
Synonyms: ICL 670-13C6
Cat. No.: HY-W740685
CAS No.: 1233196-91-2
Cat. No.: HY-CE01567
Synonyms: Deferasirox-coenzyme A
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Research Areas:
Deferasirox-CoA (Deferasirox-coenzyme A) is a coenzyme A derivative .
Cat. No.: HY-178722
CAS No.: 1266741-05-2
Deferasirox methyl ester (compound 6a), a derivative of Deferasirox (HY-17359), is an antimicrobial agent. Deferasirox methyl ester exhibits activities against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Candida albicans and Aspergillus niger with MICs of 0.5, 4.0, 1.0, 4.0, and 2.0 μg/mL, respectively. Deferasirox methyl ester can be used for antimicrobial research .
Cat. No.: HY-179052
Research Areas:
Apoptosis inducer 50 (Compound 5e) is an apoptosis inducer as well as an autophagy inducer agent. Apoptosis inducer 50 exhibits potent and selective anti-cancer activity against triple-negative breast cancer cells and metastatic colon cancer cells. Apoptosis inducer 50 upregulates the expression of pro-apoptotic proteins (Bax, Bim, cleaved Caspase-9) and downregulates the expression of the anti-apoptotic protein (BCL-XL). Apoptosis inducer 50 upregulates key autophagy markers such as Beclin-1 and ATG5, and enhances the conversion of LC3-I to LC3-II., Apoptosis inducer 50 arrests cancer cells in the G1/S phase by upregulating the expression of p21 and p27 while downregulating Cyclin D1. Apoptosis inducer 50 increases the level of ROS .
Cat. No.: HY-166458S
Cat. No.: HY-180943
CAS No.: 2568585-37-3
Research Areas:
Antiparasitic agent-39 (Compound 14) is a selective antiparasitic agent and Deferasirox (HY-17359) derivative. Antiparasitic agent-39 reduces the mitochondrial membrane potential. Antiparasitic agent-39 shows antiparasitic activity against T. brucei, T. gambiense, L. Mexicana, T. gondii, B. divergens, P. falciparum with EC50s of 4.2 nM, 10.4 nM, 52.0 nM, 17.0 nM, 41.2 nM, 54.8 nM, respectively .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
