2568585-37-3
Chemical Structure
Antiparasitic agent-39
- CAS No.: 2568585-37-3
- Formula:C49H50ClN4O3P
- Molecular Weight:809.37
InChIKey: HRRKPLWOXHVEFS-UHFFFAOYSA-N
SMILES: OC1=CC=CC=C1C2=NN(C(C3=CC=CC=C3O)=N2)C4=CC=C(C(NCCCCCCCCCC[P+](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)=O)C=C4.[Cl-]
Biological Activity: Antiparasitic agent-39 (Compound 14) is a selective antiparasitic agent and Deferasirox (HY-17359) derivative. Antiparasitic agent-39 reduces the mitochondrial membrane potential. Antiparasitic agent-39 shows antiparasitic activity against T. brucei, T. gambiense, L. Mexicana, T. gondii, B. divergens, P. falciparum with EC50s of 4.2 nM, 10.4 nM, 52.0 nM, 17.0 nM, 41.2 nM, 54.8 nM, respectively[1].
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Antiparasitic agent-39 | Antiparasitic agent-39 (Compound 14) is a selective antiparasitic agent and Deferasirox (HY-17359) derivative. Antiparasitic agent-39 reduces the mitochondrial membrane potential. Antiparasitic agent-39 shows antiparasitic activity against T. brucei, T. gambiense, L. Mexicana, T. gondii, B. divergens, P. falciparum with EC50s of 4.2 nM, 10.4 nM, 52.0 nM, 17.0 nM, 41.2 nM, 54.8 nM, respectively. | |||||||||||||||||||||
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Keywords
