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2 Results for "
EF-1502
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "EF-1502" in MCE Product Catalog:
Cat. No.: HY-118931
CAS No.: 684645-54-3
Target:
Research Areas:
EF-1502 is a potent and selective GABA transporter inhibitor with GAT1 and BGT1 inhibitory activity. EF-1502 produces a synergistic anti-epileptic effect when used in combination with Tiagabine (HY-B0696), a compound used to suppress epileptic seizures. The dosing combination of EF-1502 exhibited reduced anti-epileptic efficacy and dyskinesia when used with THIP (HY-10232). The mechanism of EF-1502 differs significantly from Tiagabine, suggesting a unique role in the inhibitory strategy .
Cat. No.: HY-118207
CAS No.: 770688-66-9
Target:
Research Areas:
LU-32-176B, a GABA transporter 1(GAT1) selective inhibitor, is found to exert a synergistic anticonvulsant action with GAT2 transport inhibitor EF1502. LU-32-176B inhibits neurons, astrocytes and mGAT1 with the IC50 values of 2μM, 1μM, 4μM, respectively .
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