1 Result for "

EGF binding pocket

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EGF binding pocket" in MCE Product Catalog:

Cat. No.: HY-P11757
CAS No.: 2251785-27-8
Target:  

EGFR

Research Areas:  

Cancer

Cyclo[K(N3)larllt] is a seven-membered cyclic peptide targeting EGFR, with a Kd value of 5.09 μM, and exhibits binding selectivity toward homologous proteins HER2 and HER3. Cyclo[K(N3)larllt] has no cytotoxicity and shows no growth inhibitory effect on cancer cells overexpressing EGFR. Cyclo[K(N3)larllt] can serve as a ligand for EGFR-targeted fluorescent conjugates, which is applicable to the detection of cancers with EGFR overexpression. Cyclo[K(N3)larllt] can be used in the research of colorectal cancer .
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