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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
EIF2AK4
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "EIF2AK4" in MCE Product Catalog:
Cat. No.: HY-W319647
CAS No.: 315705-10-3
Research Areas:
GCN2 activator-1 (Compound 20) is a GCN2 activator. GCN2 activator-1 binds within the ATP-pocket of GCN2 and activates GCN2 in a GCN1-independent manner. GCN2 activator-1 activates Integrated Stress Response (ISR) in cells. GCN2 activator-1 inhibits PKR with an IC50 of 3.75 µM. GCN2 activator-1 can be used for research of pulmonary veno-occlusive disease (PVOD) .
Target:
PROTACs CDK AAK1 Cyclin G-associated Kinase (GAK) Salt-inducible Kinase (SIK) LIM Kinase (LIMK) Wee1 SnRK
Research Areas:
RSS0680 is a small noncoding RNA (sRNA) targeting the mRNA ribosome binding site (RBS) and a PROTAC. RSS0680 competitively binds to RBS through the conserved CCUCCUCCC anti-Shine-Dalgarno (aSD) sequence and inhibits the translation initiation of target genes. RSS0680 can interact with the DUF1127 protein CcaF1, regulate its own stability and participate in bacterial oxidative stress defense, enhancing the host's resistance to heat shock and oxidative damage by affecting pathways such as C1 metabolism and pyruvate dehydrogenase complex. RSS0680 degrades AAK1, CDK1, CDK16, CDK2, CDK4, CDK6, EIF2AK4, GAK, LATSl, LIMK2, MAPK6, MAPKAPK5, MARK2, MARK4, MKNK2, NEK9, RPS6KB1, SIK2, SNRK, STK17A, STK17B, STK35, and WEEl. RSS0680 can be used to study diseases or disorders mediated by aberrant kinase activity and regulatory mechanisms of noncoding RNAs in α-proteobacteria[1][2].
Cat. No.: HY-RS04247
Target:
Research Areas:
EIF2AK4 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF2AK4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E70712
Research Areas:
EIF2AK4 Recombinant Human Active Protein Kinase belongs to a family of kinases that regulate angiogenesis in response to cellular stress. EIF2AK4 Recombinant Human Active Protein Kinase can be used for the study of pulmonary capillary hemangiomatosis (PCH) .
Cat. No.: HY-208758A
CAS No.: 1627177-37-0
Research Areas:
(S)-GCN2-IN-8 is a general control nonderepressible 2 (GCN2, EIF2AK4) inhibitor. (S)-GCN2-IN-8 inhibits signal transduction by the stress response kinase GCN2. (S)-GCN2-IN-8 can be used for the research of cancer .
Cat. No.: HY-P705590
Synonyms: EIF2AK4; Eukaryotic Translation Initiation Factor 2-Alpha Kinase 4; Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4; Non-Specific Serine/Threonine Protein Kinase; GCN2; General Control Nonderepressible 2; KIAA1338; GCN2 EIF2alpha Kinase; EIF-2-A
Species:
Source:
Cat. No.: HY-208758
CAS No.: 1627180-54-4
Research Areas:
GCN2/GSK3α-IN-1 is a GCN2 and GSK3α inhibitor with an IC50 of less than 1 μM for both targets. GCN2/GSK3α-IN-1 can be used in cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
