1 Result for "

EP-009

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EP-009" in MCE Product Catalog:

Cat. No.: HY-121874
CAS No.: 1462951-30-9
Target:  

JAK

Research Areas:  

Cancer

EP009 is a JAK3 inhibitor that selectively inhibits IL-2-mediated JAK3 tyrosine phosphorylation (IC50=10-20 μM in Kit225 cells) without affecting IL-3-induced JAK2 phosphorylation (up to 50 μM in BaF/3 cells). EP009 significantly reduced Kit225 cell viability (72 h, LD50=5.0 μM) while having no effect on BaF/3 cells. .
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