2 Results for "

ER 50891

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ER 50891" in MCE Product Catalog:

Cat. No.: HY-108531
CAS No.: 187400-85-7
Purity:  99.86%
Target:  

RAR/RXR

Research Areas:  

Metabolic Disease

ER 50891 is a RARα antagonist. ER 50891 can significantly antagonize the inhibitory effect of all-trans retinoic acid (ATRA) on the total cell metabolic activity and proliferation of MC3T3-E1 preosteoblasts. ER 50891 rescues ATRA-inhibited osteocalcin (OCN) expression and extracellular matrix mineralization, and suppresses alkaline phosphatase (ALP) activity synergistically. ER 50891 can be used for the study of osteoporosis related to ATRA-induced inhibition of osteoblastogenesis .
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Cat. No.: HY-108531A
Purity:  99.86%
Target:  

RAR/RXR

Research Areas:  

Cancer

ER 50891 quarterhydrate is a RARα antagonist. ER 50891 can significantly antagonize the inhibitory effect of all-trans retinoic acid (ATRA) on the total cell metabolic activity and proliferation of MC3T3-E1 preosteoblasts. ER 50891 rescues ATRA-inhibited osteocalcin (OCN) expression and extracellular matrix mineralization, and suppresses alkaline phosphatase (ALP) activity synergistically. ER 50891 can be used for the study of osteoporosis related to ATRA-induced inhibition of osteoblastogenesis .
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