4 Results for "

Enzyme replacement therapy

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Enzyme replacement therapy" in MCE Product Catalog:

Cat. No.: HY-108786
CAS No.: 1174277-80-5
Purity:  97.88%
Synonyms: ENB-0040

Target:  

Phosphatase

Research Areas:  

Metabolic Disease

Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2 / knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP) .
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Cat. No.: HY-P991677
CAS No.: 2770242-54-9
Synonyms: INZ-701
Efmirenpase alfa is an Fc-ENPP1 fusion protein (human IgG1 Fc domain linked to a modified human ENPP1). Efmirenpase alfa has prolonged half-life and enhanced receptor affinity compared with native human ENPP1. Efmirenpase alfa can be used as an enzyme replacement therapy for ENPP1 deficiency such as arterial calcification and hypophosphatemic rickets research .
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Cat. No.: HY-P991210
CAS No.: 2746354-58-3
Synonyms: ALXN-1850

Target:  

Phosphatase

Research Areas:  

Cardiovascular Disease

Efzimfotase alfa (ALXN-1850) is enzyme replacement therapy agent targeting the deficiency of tissue-nonspecific alkaline phosphatase (TNSALP). Efzimfotase alfa functions by hydrolyzing the substrates of TNSALP, reducing the concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5′-phosphate (PLP). Efzimfotase alfa is promising for research of hypophosphatasia (HPP) .
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Cat. No.: HY-153592
CAS No.: 850020-01-8
Purity:  ≥97.0%
Target:  

Glycosidase

Research Areas:  

Others

Therapeutic agent-1 is a heteroaryl compound that can be used in Gaucher disease glucocerebrosidase activity enzyme replacement therapy .
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