2770242-54-9
2770242-54-9
Chemical Structure
Efmirenpase alfa
Synonym(s): INZ-701
- CAS 番号: 2770242-54-9
- Formula:N/A
- Molecular Weight:N/A
SMILES: N/A
Biological Activity: Efmirenpase alfa is an Fc-ENPP1 fusion protein (human IgG1 Fc domain linked to a modified human ENPP1). Efmirenpase alfa has prolonged half-life and enhanced receptor affinity compared with native human ENPP1. Efmirenpase alfa can be used as an enzyme replacement therapy for ENPP1 deficiency such as arterial calcification and hypophosphatemic rickets research[1][2].
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Efmirenpase alfa | Efmirenpase alfa is an Fc-ENPP1 fusion protein (human IgG1 Fc domain linked to a modified human ENPP1). Efmirenpase alfa has prolonged half-life and enhanced receptor affinity compared with native human ENPP1. Efmirenpase alfa can be used as an enzyme replacement therapy for ENPP1 deficiency such as arterial calcification and hypophosphatemic rickets research. | |||||||||||||||||||||
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References
- [1]. Internacionales D C. International Nonproprietary Names for Pharmaceutical Substances (INN)[J]. WHO Drug Information, 2025, 39(2).
- [2]. Chunn LM, et al. Estimation of ENPP1 deficiency genetic prevalence using a comprehensive literature review and population databases. Orphanet J Rare Dis. 2022 Dec 2;17(1):421. [Content Brief]
