1 Result for "

F8-IL-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "F8-IL-4" in MCE Product Catalog:

Cat. No.: HY-P992000

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

F8-IL-4 is an immune cytokine targeting IL-4. F8-IL-4 specifically delivers IL-4 to inflammatory sites via binding to targets expressed on neovascular vessels. F8-IL-4 alleviates collagen-induced arthritis in mice by regulating T cell subsets and macrophage polarization. When combined with Dexamethasone (HY-14648), F8-IL-4 produces a synergistic and long-lasting therapeutic effect, and prevents arthritis recurrence after drug withdrawal by maintaining anti-inflammatory cell phenotypes and cytokine profiles. F8-IL-4 can be used in the research of collagen-induced arthritis .
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