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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
FLAG-FKBP12_NLS
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "FLAG-FKBP12_NLS" in MCE Product Catalog:
Cat. No.: HY-147196
CAS No.: 2384184-42-1
KB03-SLF is a bifunctional PROTAC, formed by conjugating the cysteine-targeting KB03 exploratory fragment with SLF (HY-114872), an FKBP12 ligand that does not support the degradation of FKBP12 NLS. KB03-SLF fails to degrade nuclear-localized FKBP12 NLS in cells, nor can it mediate the interaction between DCAF16 and FKBP12 NLS in a manner similar to KB02-SLF (HY-129610) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
