KB03-SLF
KB03-SLF (compound 6) is an electrophilic PROTAC degrader that binds to DCAF16 to degrade the nuclear protein FKBP12. KB03-SLF can be used in cancer research.
(Pink: FKBP51 and FKBP12 ligand (HY-114872); Blue: Cereblon ligand (HY-169968); Black: linker (HY-W040168)).
For research use only. We do not sell to patients.
- CAS No.: 2384184-42-1
- Formula: C50H63ClF3N5O12
- Molecular Weight:1018.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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FKBP12 |
Chemical Information
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CAS No. 2384184-42-1
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Molecular Weight 1018.51
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Formula C50H63ClF3N5O12
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SMILES
O=C([C@H]1N(CCCC1)C(C(C(C)(C)CC)=O)=O)O[C@@H](C2=CC(NC(CCOCCOCCNC(CCNC(C3=CC(NC(CCl)=O)=CC(C(F)(F)F)=C3)=O)=O)=O)=CC=C2)CCC4=CC(OC)=C(C=C4)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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