1 Result for "

FR-111142

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FR-111142" in MCE Product Catalog:

Cat. No.: HY-182569
CAS No.: 132340-44-4
Target:  

VEGFR

FR 111142 is an angiogenesis inhibitor (IC50 = 18.4 μM) and has anti-inflammatory activity (IC50 = 20.6 μM). FR 111142 inhibits capillary-like tube formation as well as nitric oxide production in LPS (HY-D1056)-activated murine macrophages. FR 111142 enhances catabolism of low-density lipoprotein (LDL). FR 111142 does not induce significant cytotoxicity in human endothelial progenitor cells, nor affect cell viability of murine macrophages. FR 111142 can be used for the research of cancer, inflammatory diseases .
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