24 Results for "

Famotidine

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "Famotidine" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-B0377
CAS No.: 76824-35-6
Synonyms: MK-208
Famotidine (MK-208) is an orally active and highly selective histamine H2 receptor antagonist. It inhibits gastric acid secretion by blocking the Gs signaling pathway, and regulates intracellular cAMP and ERK pathways. Famotidine inhibits TLR3-mediated inflammatory pathways, and reduces the expression of various inflammatory mediators and interferon-related genes. Famotidine scavenges DPPH and nitric oxide free radicals, alleviates oxidative stress damage in gastric tissue, inhibits proMMP-9, improves vascular endothelial permeability, and restores the normal physiological functions of neutrophils and eosinophils. Famotidine crosses intestinal epithelial cells via facilitated diffusion and passive diffusion, blocks paracellular cation transport, and increases intestinal transepithelial electrical resistance. Famotidine reduces serum levels of transaminases and alkaline phosphatase, exerts analgesic effects and gastric protective effects simultaneously. Famotidine can be used in studies related to COVID-19, liver injury and acute gastric ulcer .
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Cat. No.: HY-W707517
CAS No.: 2707433-64-3
Synonyms: MK-208-d4
Famotidine-d4 (MK-208-d4) is the deuterated-labeled Famotidine (HY-B0377). Famotidine (MK-208) is an orally active and highly selective histamine H2 receptor antagonist. It inhibits gastric acid secretion by blocking the Gs signaling pathway, and regulates intracellular cAMP and ERK pathways. Famotidine inhibits TLR3-mediated inflammatory pathways, and reduces the expression of various inflammatory mediators and interferon-related genes. Famotidine scavenges DPPH and nitric oxide free radicals, alleviates oxidative stress damage in gastric tissue, inhibits proMMP-9, improves vascular endothelial permeability, and restores the normal physiological functions of neutrophils and eosinophils. Famotidine crosses intestinal epithelial cells via facilitated diffusion and passive diffusion, blocks paracellular cation transport, and increases intestinal transepithelial electrical resistance. Famotidine reduces serum levels of transaminases and alkaline phosphatase, exerts analgesic effects and gastric protective effects simultaneously. Famotidine can be used in studies related to COVID-19, liver injury and acute gastric ulcer .
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Cat. No.: HY-B0377S
CAS No.: 2744683-81-4
Synonyms: MK-208-13C,d3
Famotidine- 13C,d3 (MK-208- 13C,d3) is the deuterated, 13C-labeled Famotidine (HY-B0377). Famotidine (MK-208) is an orally active and highly selective histamine H2 receptor antagonist. It inhibits gastric acid secretion by blocking the Gs signaling pathway, and regulates intracellular cAMP and ERK pathways. Famotidine inhibits TLR3-mediated inflammatory pathways, and reduces the expression of various inflammatory mediators and interferon-related genes. Famotidine scavenges DPPH and nitric oxide free radicals, alleviates oxidative stress damage in gastric tissue, inhibits proMMP-9, improves vascular endothelial permeability, and restores the normal physiological functions of neutrophils and eosinophils. Famotidine crosses intestinal epithelial cells via facilitated diffusion and passive diffusion, blocks paracellular cation transport, and increases intestinal transepithelial electrical resistance. Famotidine reduces serum levels of transaminases and alkaline phosphatase, exerts analgesic effects and gastric protective effects simultaneously. Famotidine can be used in studies related to COVID-19, liver injury and acute gastric ulcer .
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Cat. No.: HY-B0377G
CAS No.: 76824-35-6
Synonyms: MK-208 (GMP)
Famotidine GMP (MK-208 GMP) is Famotidine (HY-B0377) produced in GMP guideline. Famotidine is an orally active and highly selective histamine H2 receptor antagonist. It inhibits gastric acid secretion by blocking the Gs signaling pathway, and regulates intracellular cAMP and ERK pathways. Famotidine inhibits TLR3-mediated inflammatory pathways, and reduces the expression of various inflammatory mediators and interferon-related genes. Famotidine scavenges DPPH and nitric oxide free radicals, alleviates oxidative stress damage in gastric tissue, inhibits proMMP-9, improves vascular endothelial permeability, and restores the normal physiological functions of neutrophils and eosinophils. Famotidine crosses intestinal epithelial cells via facilitated diffusion and passive diffusion, blocks paracellular cation transport, and increases intestinal transepithelial electrical resistance. Famotidine reduces serum levels of transaminases and alkaline phosphatase, exerts analgesic effects and gastric protective effects simultaneously. Famotidine can be used in studies related to COVID-19, liver injury and acute gastric ulcer .
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Cat. No.: HY-B0377R
CAS No.: 76824-35-6
Synonyms: MK-208 (Standard)
Famotidine (Standard) (MK-208 (Standard)) is the analytical standard of Famotidine (HY-B0377). This product is intended for research and analytical applications. Famotidine (MK-208) is an orally active and highly selective histamine H2 receptor antagonist. It inhibits gastric acid secretion by blocking the Gs signaling pathway, and regulates intracellular cAMP and ERK pathways. Famotidine inhibits TLR3-mediated inflammatory pathways, and reduces the expression of various inflammatory mediators and interferon-related genes. Famotidine scavenges DPPH and nitric oxide free radicals, alleviates oxidative stress damage in gastric tissue, inhibits proMMP-9, improves vascular endothelial permeability, and restores the normal physiological functions of neutrophils and eosinophils. Famotidine crosses intestinal epithelial cells via facilitated diffusion and passive diffusion, blocks paracellular cation transport, and increases intestinal transepithelial electrical resistance. Famotidine reduces serum levels of transaminases and alkaline phosphatase, exerts analgesic effects and gastric protective effects simultaneously. Famotidine can be used in studies related to COVID-19, liver injury and acute gastric ulcer .
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Cat. No.: HY-B0377S1
Synonyms: MK-208-13C
Famotidine- 13C (MK-208- 13C) is the 13C-labeled Famotidine (HY-B0377). Famotidine (MK-208) is an orally active and highly selective histamine H2 receptor antagonist. It inhibits gastric acid secretion by blocking the Gs signaling pathway, and regulates intracellular cAMP and ERK pathways. Famotidine inhibits TLR3-mediated inflammatory pathways, and reduces the expression of various inflammatory mediators and interferon-related genes. Famotidine scavenges DPPH and nitric oxide free radicals, alleviates oxidative stress damage in gastric tissue, inhibits proMMP-9, improves vascular endothelial permeability, and restores the normal physiological functions of neutrophils and eosinophils. Famotidine crosses intestinal epithelial cells via facilitated diffusion and passive diffusion, blocks paracellular cation transport, and increases intestinal transepithelial electrical resistance. Famotidine reduces serum levels of transaminases and alkaline phosphatase, exerts analgesic effects and gastric protective effects simultaneously. Famotidine can be used in studies related to COVID-19, liver injury and acute gastric ulcer .
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Cat. No.: HY-W777002
CAS No.: 1185241-48-8
Synonyms: MK-208-13C3
Famotidine- 13C3 (MK-208- 13C3) is the 13C3-labeled Famotidine (HY-B0377). Famotidine (MK-208) is an orally active and highly selective histamine H2 receptor antagonist. It inhibits gastric acid secretion by blocking the Gs signaling pathway, and regulates intracellular cAMP and ERK pathways. Famotidine inhibits TLR3-mediated inflammatory pathways, and reduces the expression of various inflammatory mediators and interferon-related genes. Famotidine scavenges DPPH and nitric oxide free radicals, alleviates oxidative stress damage in gastric tissue, inhibits proMMP-9, improves vascular endothelial permeability, and restores the normal physiological functions of neutrophils and eosinophils. Famotidine crosses intestinal epithelial cells via facilitated diffusion and passive diffusion, blocks paracellular cation transport, and increases intestinal transepithelial electrical resistance. Famotidine reduces serum levels of transaminases and alkaline phosphatase, exerts analgesic effects and gastric protective effects simultaneously. Famotidine can be used in studies related to COVID-19, liver injury and acute gastric ulcer .
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Cat. No.: HY-Z7625
CAS No.: 89268-62-2
Synonyms: Famotidine dimer
Target:  

Drug Intermediate

Research Areas:  

Others

Famotidine impurity 5 (Famotidine dimer) is an impurity of Famotidine.
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Cat. No.: HY-Z7627
CAS No.: 129083-44-9
Synonyms: Famotidine disulfide
Target:  

Drug Intermediate

Research Areas:  

Others

Famotidine impurity 7 (Famotidine disulfide) is an impurity of Famotidine.
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Cat. No.: HY-Z8122
CAS No.: 107880-74-0
Synonyms: Famotidine propionic acid
Target:  

Drug Intermediate

Research Areas:  

Others

Famotidine impurity 8 (Famotidine propionic acid) is an impurity of Famotidine.
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Cat. No.: HY-Z8123
CAS No.: 76823-97-7
Synonyms: Famotidine cyanoamidine
Target:  

Drug Intermediate

Research Areas:  

Others

Famotidine impurity 9 (Famotidine cyanoamidine) is an impurity of Famotidine.
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Cat. No.: HY-Z7653
CAS No.: 88061-72-7
Synonyms: Famotidine impurity A hydrochloride
Target:  

Drug Intermediate

Research Areas:  

Others

Famotidine impurity 2 hydrochloride (Famotidine impurity A hydrochloride) is an impurity of Famotidine hydrochloride.
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Cat. No.: HY-Z12019
CAS No.: 124646-10-2
Synonyms: Famotidine impurity A
Target:  

Drug Intermediate

Research Areas:  

Others

Famotidine impurity 2 (Famotidine impurity A) is an impurity of Famotidine.
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Cat. No.: HY-Z11421
CAS No.: 106433-44-7
Synonyms: Famotidine impurity C
Target:  

Drug Intermediate

Research Areas:  

Others

Famotidine impurity 3 (Famotidine impurity C) is an impurity of Famotidine.
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Cat. No.: HY-Z7626
CAS No.: 76824-17-4
Synonyms: Famotidine impurity C hydrochloride
Target:  

Drug Intermediate

Research Areas:  

Others

Famotidine impurity 3 hydrochloride (Famotidine impurity C hydrochloride) is an impurity of Famotidine hydrochloride.
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Cat. No.: HY-Z8125
CAS No.: 1020719-36-1
Synonyms: Famotidine impurity I
Target:  

Drug Intermediate

Research Areas:  

Others

Famotidine impurity 1 (Famotidine impurity I) is an impurity of Famotidine.
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Cat. No.: HY-W585925
CAS No.: 90237-03-9
Target:  

Drug Intermediate

Research Areas:  

Others

Famotidine impurity 12 is an impurity of Famotidine.
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Cat. No.: HY-W560716
CAS No.: 81152-53-6
Target:  

Drug Intermediate

Research Areas:  

Others

Famotidine impurity 4 is an impurity of Famotidine.
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Cat. No.: HY-W707168
CAS No.: 76823-94-4
Target:  

Drug Intermediate

Research Areas:  

Others

Famotidine impurity 11 is an impurity of Famotidine.
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Cat. No.: HY-Z6582
CAS No.: 76824-16-3
Target:  

Drug Intermediate

Research Areas:  

Others

Famotidine impurity 6 is an impurity of Famotidine.
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