7 Results for "

G4-kappa

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "G4-kappa" in MCE Product Catalog:

Cat. No.: HY-P990089
CAS No.: 2642374-04-5
Synonyms: Getagozumab; GMA-301

Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

Patecibart is a humanized immunoglobulin G4-kappa, anti-EDNRA monoclonal antibody. Patecibart is an endothelin receptor antagonist .
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Cat. No.: HY-P990092
CAS No.: 2723442-10-0

Research Areas:  

Cancer

Rolistobart is a humanized immunoglobulin G4-kappa, anti-LILRB4/CD85k monoclonal antibody. Rolistobart is an immunostimulant and antineoplastic .
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Cat. No.: HY-P990068
CAS No.: 2643331-31-9
Synonyms: SRF617

Target:  

NTPDase

Research Areas:  

Inflammation/Immunology Cancer

Perenostobart (SRF617) is a human IgG4 antibody with inhibitory activity against CD39 ATPase. Perenostobart inhibits CD39-mediated hydrolysis of extracellular ATP to AMP, with IC50 values of 1.9 nM (HEK293 OE cells), 0.7 nM (MOLP-8 cells), and 1.2 nM (RBC-lysed whole blood). Perenostobart enhances CD4 + T-cell proliferation, promotes dendritic cell maturation, and boosts inflammasome activation in macrophages in the presence of ATP. Perenostobart demonstrates significant single-agent anti-tumor efficacy in MOLP-8 and H520 xenograft models. Perenostobart can be used for the study of cancer .
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Cat. No.: HY-P990074
CAS No.: 2651230-53-2
Synonyms: SG-001

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology

Enlonstobart is a human immunoglobulin G4-kappa, anti-PDCD1 monoclonal antibody. Enlonstobart is an immunostimulant and antineoplastic .
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Cat. No.: HY-P990081
CAS No.: 2669063-84-5
Synonyms: TB-006

Target:  

Inhibitory Antibodies

Research Areas:  

Neurological Disease

Oloctinebart is a humanized immunoglobulin G4-kappa, anti-LGALS3 monoclonal antibody. Oloctinebart is used for reduction of amyloid beta oligomers formation .
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Cat. No.: HY-P99767
CAS No.: 2210314-30-8
Synonyms: ALXN1007; Lendalizumab

Target:  

Complement System

Research Areas:  

Infection

Olendalizumab (ALXN1007) is a mouse-derived and humanized IgG2-G4-κ antibody, targeting to Complement protein C5a (Ki=60 pM). Olendalizumab targets the complement inflammatory pathway. Moreover, Olendalizumab can be used for research of complement mediated disorder caused by corona virus .
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Cat. No.: HY-P991152
CAS No.: 2956767-43-2
Synonyms: QX-005N

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Oturkibart is a humanized immunoglobulin G4-κ monoclonal antibody targeting the human interleukin 4 receptor (IL4R). Oturkibart is promising for research of inflammatory diseases, such as asthma and atopic dermatitis .
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