1 Result for "

GAT 564

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GAT 564" in MCE Product Catalog:

Cat. No.: HY-144705
CAS No.: 2851895-01-5
Target:  

Cannabinoid Receptor

Research Areas:  

Neurological Disease

GAT564 (Compound 15d) is a potent allosteric modulator of cannabinoid 1 receptor (CB1R) with EC50s of 87 and 320 nM respectively for cAMP and β-arrestin2. GAT564 markedly promotes orthosteric ligand binding to hCB1R. GAT564 is efficacious as a topical agent that significantly reduces intraocular pressure (IOP) in the ocular normotensive murine model of glaucoma .
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