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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
GATA4
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "GATA4" in MCE Product Catalog:
Cat. No.: HY-128326
CAS No.: 2362525-64-0
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ZAK-IN-1 is an orally active and selective selective leucine-zipper and sterile‑α motif kinase (ZAK) inhibitor with IC50 of 4 nM and KD of 8 nM. ZAK-IN-1 exhibits excellent selectivity against a panel of 403 wild-type kinases. ZAK-IN-1 blocks p38/GATA-4 and JNK/c-Jun signaling and shows promising anti antihypertrophic cardiomyopathy (HCM) efficacy. ZAK-IN-1 can be used for the study of HCM .
Cat. No.: HY-RS18176
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Gata4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gata4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-174673
Human GATA4 mRNA encodes the human GATA binding protein 4 (GATA4) protein, a member of the GATA family of zinc-finger transcription factors. GATA4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. It is also necessary for normal testicular development.
Cat. No.: HY-174481
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Mouse Gata4 mRNA encodes the mouse GATA binding protein 4 (Gata4) protein, a transcriptional activator that binds to the consensus sequence 5''-AGATAG-3'' and plays a key role in cardiac development.
Cat. No.: HY-RS05292
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GATA4 Human Pre-designed siRNA Set A contains three designed siRNAs for GATA4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24650
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Gata4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gata4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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GATA4-NKX2-5-IN-1 (Compound 3) dose-dependently inhibits the GATA4–NKX2-5 transcriptional synergy with an IC50 of 3 μM. GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression .
Cat. No.: HY-103484R
CAS No.: 544681-96-1
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GATA4-NKX2-5-IN-1 (Standard) is the analytical standard of GATA4-NKX2-5-IN-1 (HY-103484). This product is intended for research and analytical applications. GATA4-NKX2-5-IN-1 (Compound 3) dose-dependently inhibits the GATA4–NKX2-5 transcriptional synergy with an IC50 of 3 μM. GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
