1 Result for "

GDC3280

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GDC3280" in MCE Product Catalog:

Cat. No.: HY-160851
CAS No.: 1590403-33-0
Synonyms: AK3287; AKEX0011
Target:  

ASK1 p38 MAPK

Research Areas:  

Inflammation/Immunology

GDC-3280 (AK3287; AKEX0011) is an orally active compound based on Pirfenidone (HY-B0673)'s phenyl pyridone scaffold. GDC-3280 alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 MAPK pathway and regulating macrophage polarization. GDC-3280 exhibits anti-inflammatory and anti-fibrotic effects .
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