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GFAT1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Endogenous Metabolite (1) OGT (1) Small Interfering RNA (siRNA) (3)
By Research Areas:	Metabolic Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

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UDP-glucosamine disodium	OGT Endogenous Metabolite	Metabolic Disease
UDP-glucosamine (UDP-GlcNAc) disodium is a substrate for O-GlcNAc transferase, which catalyzes the attachment of O-GlcNAc to proteins. O-GlcNAcase catalyzes the removal of O-GlcNAc from proteins. UDP-glucosamine (UDP-GlcNAc) disodium is the end product of the hexosamine biosynthesis pathway, which is regulated primarily by glucose-6-phosphate-Glutamine:fructose-6-phosphate amidotransferase (GFAT) .

GFPT1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
GFPT1 Human Pre-designed siRNA Set A contains three designed siRNAs for GFPT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gfpt1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Gfpt1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gfpt1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gfpt1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Gfpt1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gfpt1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

UDP-glucosamine disodium	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	OGT Endogenous Metabolite
UDP-glucosamine (UDP-GlcNAc) disodium is a substrate for O-GlcNAc transferase, which catalyzes the attachment of O-GlcNAc to proteins. O-GlcNAcase catalyzes the removal of O-GlcNAc from proteins. UDP-glucosamine (UDP-GlcNAc) disodium is the end product of the hexosamine biosynthesis pathway, which is regulated primarily by glucose-6-phosphate-Glutamine:fructose-6-phosphate amidotransferase (GFAT) .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P76359

	GFPT1 Protein, Human Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1; GFAT1; GFAT; GFPT	Human	E. coli
	As a key regulator of glucose influx into the hexosamine pathway, the GFPT1 protein plays a key role in controlling the availability of protein N- and O-linked glycosylation precursors. In addition, GFPT1 is involved in the regulation of circadian expression of clock genes BMAL1 and CRY1 and contributes to the complex regulation of cytoplasmic UDP-GlcNAc metabolic fluctuations. GFPT1 Protein, Human is the recombinant human-derived GFPT1 protein, expressed by E. coli , with tag free.

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Host:	Mouse (2) Rabbit (2)
Reactivity:	Human (4) Rat (2) Monkey (2)
Application:	IHC-P (2) ICC/IF (2) IP (2) WB (4) FC (2) ELISA (2)
Isotype:	IgG (2) IgG1 (2)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

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HY-P84494

	GFPT1 Antibody (YA4191) GFA; GFAT; GFPT; MSLG; CMS12; GFAT1; CMSTA1; GFAT 1; GFAT1m; GFPT1L	WB, ICC/IF, FC, ELISA	Human, Rat, Monkey
	GFPT1 Antibody (YA4191) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GFPT1.

HY-P84494A

	GFPT1 Antibody (YA4191)(PBS only) GFA; GFAT; GFPT; MSLG; CMS12; GFAT1; CMSTA1; GFAT 1; GFAT1m; GFPT1L	WB, ICC/IF, FC, ELISA	Human, Rat, Monkey
	GFPT1 Antibody (YA4191) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GFPT1.

HY-P83167

	GFPT1 Antibody (YA2912) GFA; GFAT; GFPT; MSLG; CMS12; GFAT1; CMSTA1; GFAT 1; GFAT1m; GFPT1L	WB, IHC-P, IP	Human
	GFPT1 Antibody (YA2912) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GFPT1.

HY-P83167A

	GFPT1 Antibody (YA2912)(PBS only) GFA; GFAT; GFPT; MSLG; CMS12; GFAT1; CMSTA1; GFAT 1; GFAT1m; GFPT1L	WB, IHC-P, IP	Human
	GFPT1 Antibody (YA2912) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GFPT1.

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Cat. No.	Product Name		Classification

HY-RS05384

GFPT1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
GFPT1 Human Pre-designed siRNA Set A contains three designed siRNAs for GFPT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS25494

Gfpt1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Gfpt1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gfpt1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS19005

Gfpt1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Gfpt1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gfpt1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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