1 Result for "

GNE783

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GNE783" in MCE Product Catalog:

Cat. No.: HY-15882
CAS No.: 1200127-66-7
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

GNE-783 is a selective CHK1 inhibitor that enhances the activity of gemcitabine. GNE-783 improves the efficacy of anti-metabolite DNA damage drugs by inactivating S-phase and G2-phase cell cycle checkpoints following DNA damage. GNE-783 selectively enhances the chemical synergy of certain drugs in different tumor types, for example, enhancing the activity of temozolomide only in melanoma cell lines .
loading...
    loading...