1 Result for "

GS1291269

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GS1291269" in MCE Product Catalog:

Cat. No.: HY-180921
CAS No.: 2845278-33-1
Target:  

Ketohexokinase

Research Areas:  

Metabolic Disease Endocrinology

GS-1291269 is a potent and neutral ketohexokinase (KHK) inhibitor, with IC50s of 0.38 and 2.1 nM against KHK-C and KHK-A, respectively. GS-1291269 demonstrates liver and kidney fructose-1-phosphate (F1P) reduction in a fructose challenge model in rats. GS-1291269 can be used for kidney disease and metabolic-dysfunction-associated steatotic liver disease (MASLD) research .
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