1 Result for "

GTCpFE

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GTCpFE" in MCE Product Catalog:

Cat. No.: HY-164480
CAS No.: 1588866-45-8
Target:  

IKK NF-κB

Research Areas:  

Inflammation/Immunology Cancer

GTCpFE inhibits IKKα/β in the NF-κB pathway with anti-inflammatory activities and blocks p65 nuclear entry, which consists of Dimethyl fumarate (DMF) (HY-17363) linked to Aspirin (ASA) (HY-14654). GTCpFE exhibits selective anti-cancer stem-like cell (CSC) activity by reducing mammosphere growth and the CD44 + CD24 - immunophenotype. GTCpFE inhibits breast cancer stem cells, an important NFκB- and PGE2-dependent phenotype in aggressive cancers .
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