GTCpFE
GTCpFE inhibits IKKα/β in the NF-κB pathway with anti-inflammatory activities and blocks p65 nuclear entry, which consists of Dimethyl fumarate (DMF) (HY-17363) linked to Aspirin (ASA) (HY-14654). GTCpFE exhibits selective anti-cancer stem-like cell (CSC) activity by reducing mammosphere growth and the CD44+ CD24- immunophenotype. GTCpFE inhibits breast cancer stem cells, an important NFκB- and PGE2-dependent phenotype in aggressive cancers.
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- CAS No.: 1588866-45-8
- Formule: C22H20O8
- Masse moléculaire:412.39
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Help & FAQs
Activité biologique
Description
Chemical Information
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CAS No. 1588866-45-8
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Masse moléculaire 412.39
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Formule C22H20O8
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SMILES
O=C(OC1=CC=C(COC(/C=C/C(OCC)=O)=O)C=C1)C2=C(OC(C)=O)C=CC=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GTCpFE Related Classifications
HY-164480 Related Classifications
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