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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
GZMB
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "GZMB" in MCE Product Catalog:
Cat. No.: HY-161982
CAS No.: 3079468-41-7
Target:
Research Areas:
JNU-0921 is a potent and orally active CD137 agonist. JNU-0921 increases the mRNA expression of IFN-γ and GZMB. JNU-0921 induces luciferase activity with an EC50 value of 64.07 nM.JNU-0921 enhances effector and memory function of cytotoxic CD8 + T cells (CTLs) and alleviates their exhaustion. JNU-0921 also skews polarization of helper T cells toward T helper 1 type and enhances their activity to boost CTL function. JNU-0921 shows anticancer activity .
Cat. No.: HY-RS05940
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Research Areas:
GZMB Human Pre-designed siRNA Set A contains three designed siRNAs for GZMB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-149916
CAS No.: 2922920-71-4
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Research Areas:
A2AR-antagonist-1 (compound 38) is an orally active adenosine A2A receptor (A2AR) antagonist (IC50=29 nM). A2AR-antagonist-1 exhibits anti-tumor activity and mouse liver microsomal metabolic stability (t1/2=86.1 min). A2AR-antagonist-1 is also a T cells activator, via inhibiting immunosuppressive molecules (LAG-3 and TIM-3) and enhancing effector molecules (GZMB, IFNG, and IL-2) .
Cat. No.: HY-RS17266
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Research Areas:
Gzmb Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gzmb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23720
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Research Areas:
Gzmb Rat Pre-designed siRNA Set A contains three designed siRNAs for Gzmb gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P703940
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Granzyme B; CTLA-1; CCP1; Fragmentin-2; GZMB
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
