2 Results for "

Gefitinib-d8

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Gefitinib-d8" in MCE Product Catalog:

Cat. No.: HY-50895S
CAS No.: 857091-32-8
Synonyms: ZD1839-d8
Gefitinib-d8 (ZD1839-d8) is a deuterium labeled Gefitinib. Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells .
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Cat. No.: HY-100064S
CAS No.: 2748500-39-0
Purity:  99.84%
O-Desmethyl gefitinib-d8 is a deuterium labeled O-Desmethyl gefitinib. O-Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O-desmethyl gefitinib is dependent on CYP2D6 activity. O-desmethyl gefitinib inhibits EGFR with an IC50 of 36 nM in subcellular assays .
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