1 Result for "

Glu664

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Glu664" in MCE Product Catalog:

Cat. No.: HY-185227
CAS No.: 1394837-94-5
Research Areas:  

Cancer

EphB4-IN-1 is a selective EphB4 tyrosine kinase inhibitor with IC50 values of 0.16-0.30 μM. EphB4-IN-1 binds to the ATP binding site of EphB4 in a DFG-in conformation, forming four stable intermolecular hydrogen bonds. EphB4-IN-1 also inhibits Src, Abl1, Lck, and EGFR kinases. EphB4-IN-1 inhibits EphB4 autophosphorylation. EphB4-IN-1 can be used for the research of cancer, such as non small cell lung cancer .
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