1 Result for "

Glucuronidase responsive linker

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Glucuronidase responsive linker" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-128943
CAS No.: 2246380-69-6
Purity:  98.49%
Research Areas:  

Cancer

MAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) agent linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively.Albumin-coupled MAC glucosidol-linked SN-38 shows good stability in mouse plasma .
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