2. Search Result
Search Result
Results for "

Gpr52 agonist

" in MedChemExpress (MCE) Product Catalog:
Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101787
    TP-024
    2 Publications Verification

    FTBMT

    		 GPR52 Neurological Disease
    TP-024 (FTBMT), a chemical probe, is a selective GPR52 agonist with an EC50 of 75 nM . TP-024 has antipsychotic and procognitive properties .
    TP-024
  • HY-147395
    GPR52 agonist-1

    		GPR52 Neurological Disease
    GPR52 agonist-1 is a potent, orally active and blood-brain barrier (BBB) penetrant GPR52 agonist with an pEC50 value of 7.53. GPR52 agonist-1 affects cAMP accumulation through direct interaction with GPR52. GPR52 agonist-1 can significantly suppress Methamphetamine-induced hyperactivity in mice. Antipsychotic activity .
    GPR52 agonist-1
  • HY-138639
    PW0787
    1 Publications Verification

    		 GPR52 Neurological Disease
    PW0787 is a potent, selective, orally active, and brain-penetrant GPR52 agonist (EC50=135 nM). PW0787 suppresses psychostimulant behavior .
    PW0787
  • HY-176900
    GPR52 agonist-4

    		GPR52 Neurological Disease
    GPR52 agonist-4 (Compound 65) is a highly selective G-protein-coupled receptor GPR52 modulator. GPR52 agonist-4 is promising for research of neuropsychiatric diseases .
    GPR52 agonist-4
  • HY-154980
    NXE0041178

    		GPR52 Neurological Disease
    NXE0041178 is an orally active and BBB-penetrant full GPR52 agonist, with a pEC50 of 7.5 for human GPR52 and an EC50 of 27.5 nM (pEC50 = 7.55) for rat GPR52. NXE0041178 shows no significant inhibition on hERG, hNaV1.5 and cytochrome P450 isoforms. NXE0041178 can reduce d-amphetamine-induced hyperactivity in rats. NXE0041178 can be used for research of Neurological disease .
    NXE0041178
  • HY-163671
    PW0729

    		GPR52 Neurological Disease
    PW0729 (compound 15b) is an orphan GPR52 agonist with potential applications in GPR52 activation, signaling bias, and neuropsychiatric and neurological disorders. The brain exposure characteristics of PW0729 need to be further optimized .
    PW0729
  • HY-183945
    WO-459

    		Mas-related G-protein-coupled Receptor (MRGPR) Neurological Disease
    WO-459 is a potent Gpr52 agonist. WO-459 induces dose-dependent elevation of intracellular cAMP in cells expressing Gpr52. WO-459 can be used for the research of Huntington’s disease and psychotic disorders .
    WO-459
  • HY-101787R
    TP-024 (Standard)

    FTBMT (Standard)

    		 Reference Standards GPR52 Neurological Disease
    TP-024 (Standard) (FTBMT (Standard)) is the analytical standard of TP-024 (HY-101787). This product is intended for research and analytical applications. TP-024 (FTBMT), a chemical probe, is a selective GPR52 agonist with an EC50 of 75 nM . TP-024 has antipsychotic and procognitive properties .
    TP-024 (Standard)

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: