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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
H838 cells
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "H838 cells" in MCE Product Catalog:
Cat. No.: HY-163428
CAS No.: 2414056-31-6
Synonyms: ZN-A-1041
Target:
Research Areas:
ZN-A-1041 inhibits HER2 in BT474 cell and wt-EGFR in H838 cells, with IC50s of 9.5 nM and 12 μM respectively. ZN-A-1041 can be used for research of cancer and inflammation .
Cat. No.: HY-168847
CAS No.: 2923669-20-7
INCB159020 is an orally active KRAS G12D inhibitor with equivalent binding potency for the active GTP-bound and inactive GDP-bound forms of KRAS G12D. INCB159020 can be used in the research of KRAS-driven cancers .
Cat. No.: HY-184673
CAS No.: 3086248-19-0
Target:
Research Areas:
SMD-6346 is an orally active SMARCA2 PROTAC degrader with a DC50 of 3.3 nM. SMD-6346 induces SMARCA2 degradation and exhibits extremely low activity against SMARCA4. SMD-6346 inhibits the growth of SMARCA4-deficient cancer cells and suppresses tumor growth in mouse xenograft models. SMD-6346 can be used for the research of non-small cell lung cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
