2923669-20-7
2923669-20-7
Chemical Structure
INCB159020
- CAS 番号: 2923669-20-7
- Formula:C37H35ClFN7O2
- Molecular Weight:664.17
InChIKey: BZTYAVYCLPPSMR-MGRYNLJHSA-N
SMILES: ClC1=C(C(C2=C(C3=NC(C4=NC=C(N=C4)C)=C5C(N([C@@H]6[C@@H]7NC[C@H]6C7)C([C@H](N8C(COCC8)=O)C)=C5)=C3C=C2CCC#N)F)=CC=C1)C
Biological Activity: INCB159020 is an orally active KRASG12D inhibitor with equivalent binding potency for the active GTP-bound and inactive GDP-bound forms of KRASG12D. INCB159020 can be used in the research of KRAS-driven cancers[1].
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INCB159020 | INCB159020 is an orally active KRASG12D inhibitor with equivalent binding potency for the active GTP-bound and inactive GDP-bound forms of KRASG12D. INCB159020 can be used in the research of KRAS-driven cancers. | |||||||||||||||||||||
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References
Keywords
