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NNMT-IN-3 

Cat. No.: HY-151193
Handling Instructions

NNMT-IN-3 (compound 14) is a potent and selective nicotinamide N-methyltransferase NNMT inhibitor with IC50 values of 1.1 nM and 0.4 μM in cell-free and cell-based assays, respectively. NNMT-IN-3 can be used to research obesity, type 2 diabetes, alcohol-related liver disease, cancer, sarcopenia and so on.

For research use only. We do not sell to patients.

NNMT-IN-3 Chemical Structure

NNMT-IN-3 Chemical Structure

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Description

NNMT-IN-3 (compound 14) is a potent and selective nicotinamide N-methyltransferase NNMT inhibitor with IC50 values of 1.1 nM and 0.4 μM in cell-free and cell-based assays, respectively. NNMT-IN-3 can be used to research obesity, type 2 diabetes, alcohol-related liver disease, cancer, sarcopenia and so on[1].

IC50 & Target

IC50: 1.1 nM (NNMT, cell-free), 0.4 μM (NNMT, cell-based)[1]

Molecular Weight

592.13

Formula

C34H34ClN7O

SMILES

CC1=CC=C2C(C=C(N2CC3=CC=C(C=C3)Cl)[[email protected]]4C[[email protected]@H](CN4C(C5=CC6=C(NC(C)=C6)N=C5)=O)N7N=C(C=C7CN)C)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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NNMT-IN-3
Cat. No.:
HY-151193
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