3031493-74-7
3031493-74-7
Chemical Structure
NNMT-IN-3
- CAS No.: 3031493-74-7
- Formula:C34H34ClN7O
- Molecular Weight:592.13
IUPAC Name: pentanoic-3,3-d2 acid
InChIKey: LJMIMBZGIMDSPE-BHDXBOSCSA-N
SMILES: CC1=CC=C2C(C=C(N2CC3=CC=C(C=C3)Cl)[C@H]4C[C@@H](CN4C(C5=CC6=C(NC(C)=C6)N=C5)=O)N7N=C(C=C7CN)C)=C1
Biological Activity: NNMT-IN-3 (Compound 14) is a potent and selective nicotinamide N-methyltransferase (NNMT) inhibitor, with IC50 values of 1.1 nM and 0.4 μM in cell-free and cell-based assays, respectively. NNMT-IN-3 can be used in the research of diseases such as obesity, type 2 diabetes and cancer[1].
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NNMT-IN-3 | NNMT-IN-3 (Compound 14) is a potent and selective nicotinamide N-methyltransferase (NNMT) inhibitor, with IC50 values of 1.1 nM and 0.4 μM in cell-free and cell-based assays, respectively. NNMT-IN-3 can be used in the research of diseases such as obesity, type 2 diabetes and cancer. | |||||||||||||||||||||
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References
Keywords
