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Cat. No.: HY-172626

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KRAS G12D inhibitor 28

KRAS G12D inhibitor 28 is a KRAS^G12D inhibitor. KRAS G12D inhibitor 28 can be used in the cancer research.

For research use only. We do not sell to patients.

CAS No.: 2923669-28-5
Formula: C₃₅H₃₂Cl₂FN₅O
Molecular Weight:628.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

KRAS G12D inhibitor 28 Chemical Structure

CAS No.: 2923669-28-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

KRAS G12D inhibitor 28 is a KRAS^G12D inhibitor. KRAS G12D inhibitor 28 can be used in the cancer research^[1].

IC₅₀ & Target^[1]

KRas G12D

All Ras Isoforms :

In Vitro

KRAS G12D inhibitor 28 (Compound 1) inhibits KRAS^G12D^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2923669-28-5
Molecular Weight 628.57
Formula C₃₅H₃₂Cl₂FN₅O
SMILES

ClC1=C(Cl)C(C2=C(F)C(N=C(C)C3=C4N([C@H]5[C@H]6CN[C@@H]5C6)C([C@@H]7N(C(C8CC8)=O)[C@H]9[C@H](C9)C7)=C3)=C4C=C2CCC#N)=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jiemin HU, et al. Crystalline forms of 3-(1-(( 1 r,4r,5s)-2-azabicyclo[2.1.1 ]hexan-5-yl)-2-(( 1 r,3r,5r)-2-( cyclopropanecarbonyl)-2-azabicyclo[3.1.0]hexan-3-yl)-7-(2,3-dichlorophenyl)-6-fluoro-4-methyl-1 h-pyrrolo[3,2-c]quinolin-8-yl)propanenitrile.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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KRAS G12D inhibitor 28

All Ras Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

KRAS G12D inhibitor 28 Related Classifications

HY-172626 Related Classifications