TTK inhibitor 3
TTK inhibitor 3 is a potent and selective TTK (an essential spindle assembly checkpoint enzyme) inhibitor with an IC50 value of 3.0 nM.
For research use only. We do not sell to patients.
- CAS No.: 2820453-41-4
- Formula: C42H49N9O3
- Molecular Weight:727.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CAL-51 | IC50 |
0.016 μM
Compound: 25
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Antiproliferative activity against human CAL-51 cells assessed as inhibition of cell proliferation measured after 3 days by Cell Titer-Glo luminescence based assay
Antiproliferative activity against human CAL-51 cells assessed as inhibition of cell proliferation measured after 3 days by Cell Titer-Glo luminescence based assay
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[PMID: 34459599] |
Chemical Information
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CAS No. 2820453-41-4
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Molecular Weight 727.90
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Formula C42H49N9O3
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SMILES
O=C1C2=CC(C3=C4C(NC=C4)=NC(NC5=CC=C(N6CCC(C(N7CC8(CN(C)C8)C7)=O)CC6)C=C5OC)=N3)=CN2CCN1C9=C(CC)C=CC=C9CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TTK inhibitor 3 Related Classifications
HY-132884 Related Classifications
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