TTK inhibitor 3
TTK inhibitor 3 is a potent and selective TTK (an essential spindle assembly checkpoint enzyme) inhibitor with an IC50 value of 3.0 nM.
For research use only. We do not sell to patients.
- CAS No.: 2820453-41-4
- Formula: C42H49N9O3
- Molecular Weight:727.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CAL-51 | IC50 |
0.016 μM
Compound: 25
|
Antiproliferative activity against human CAL-51 cells assessed as inhibition of cell proliferation measured after 3 days by Cell Titer-Glo luminescence based assay
Antiproliferative activity against human CAL-51 cells assessed as inhibition of cell proliferation measured after 3 days by Cell Titer-Glo luminescence based assay
|
[PMID: 34459599] |
Chemical Information
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CAS No. 2820453-41-4
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Molecular Weight 727.90
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Formula C42H49N9O3
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SMILES
O=C1C2=CC(C3=C4C(NC=C4)=NC(NC5=CC=C(N6CCC(C(N7CC8(CN(C)C8)C7)=O)CC6)C=C5OC)=N3)=CN2CCN1C9=C(CC)C=CC=C9CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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