2 Results for "

HPAFII cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "HPAFII cells" in MCE Product Catalog:

Cat. No.: HY-155542
CAS No.: 3049676-15-2
Target:  

ROR

Research Areas:  

Cancer

RORγ antagonist 1 (compound 22), a potent betulinic acid derivative, is an antagonist of RORγ (KD=0.18 μM). RORγ antagonist 1 exhibits anti-proliferative activity in HPAF-II pancreatic cancer xenograft model. RORγ antagonist 1 inhibits RAS/MAPK and AKT/mTORC1 pathway, and induces caspase-dependent apoptosis in pancreatic cancer cells .
loading...
    loading...
Cat. No.: HY-168847
CAS No.: 2923669-20-7
Target:  

Ras

Research Areas:  

Cancer

INCB159020 is an orally active KRAS G12D inhibitor with equivalent binding potency for the active GTP-bound and inactive GDP-bound forms of KRAS G12D. INCB159020 can be used in the research of KRAS-driven cancers .
loading...
    loading...