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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
His353
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "His353" in MCE Product Catalog:
Cat. No.: HY-164891
CAS No.: 2839138-44-0
Target:
Research Areas:
EM12-FS is a cereblon (CRBN) ligand that binds CRBN at His353 and a molecular glue degrader of NTAQ1. EM12-FS has a human plasma half-life of 196 min .
Cat. No.: HY-W760183
CAS No.: 2803819-61-4
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Research Areas:
EM12-SO2F is a powerful covalent inhibitor of CRBN through binding at His353. EM12-SO2F is a useful chemical probe to investigate the CRBN. EM12-SO2F inhibits the degradation of IKZF1 by lenalidomide (HY-A0003) in MOLT4 cells
Cat. No.: HY-188063
CAS No.: 161128-65-0
3-Deazahomoneplanocin A is an S-adenosylhomocysteine (AdoHcy) hydrolase inhibitor with an IC50 of 3.76 μM. 3-Deazahomoneplanocin A exhibits antiviral activity against VSV. It also shows anticancer activity against lung cancer, colon cancer, breast cancer, liver cancer and gastric cancer .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
