1 Result for "

IAG 10

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "IAG 10" in MCE Product Catalog:

Cat. No.: HY-180392
CAS No.: 2361305-69-1
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

IAG-10 is a selective DNA polymerase kappa (hpol κ) inhibitor with an IC50 value of 7.2 μM. IAG-10 exerts its function by disrupting the formation of the binary complex between the enzyme and DNA. IAG-10 enhances the antiproliferative and DNA-damaging activities of Temozolomide (HY-17364) in tumor cells with functional hpol κ expression. IAG-10 can be used in the research of cancers such as malignant brain tumors .
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